Next Generation Sequencing (NGS) is a massively parallel sequencing method that has revolutionized medical informatics and precision medicine. This cost-effective and high-throughput technique makes it possible to rapidly catalogue genomes, transcriptomes, and genetic variants. With NGS, we offer you a powerful tool to leverage your clinical data. For assigning clinical trial patients to treatments that target unique conditions (e.g. a tumor-specific mutation), Technical Resources International, Inc. (TRI) uses NGS data to classify tumors, identify biomarkers, and support diagnostics which can lead to actionable results.
TRI’s Ph.D. bioinformaticians and computer scientists support whole exome sequencing (WES), whole genome sequencing (WGS), and identification of single nucleotide polymorphisms (SNPs) with faster turnaround and higher accuracy than other providers.
- Healthcare and Precision Medicine
NGS is redefining many aspects of clinical and non-clinical research, and paving the way for personalized medicine. TRI uses NGS data from WES, WGS, RNA-Seq, cancer panels, and rare disease panels to classify tumors, identify biomarkers, and support diagnostics. The resulting pharmacogenomic data can be used to tailor individualized treatment plans that maximize efficacy and safety.
TRI designs, develops, and implements cutting-edge bioinformatics solutions utilizing genomics, transcriptomics, and proteomics data. TRI performs genome assembly, gene annotation, SNP identification, and pathway analysis, and is equipped to run DNA-seq, RNA-seq and CHIP-seq. Our in-house NGS pipeline allows for project optimization and assists researchers in their quest for bioinformatics solutions and breakthrough discoveries.
Clinical Trial Support
The use of NGS in a clinical trial can pose logistical and scientific challenges. TRI works with clinical trial sponsors to select the most cost-effective and appropriate sequencing technologies that will generate the data necessary for your study needs. Our tools are 21 CFR part 11 compliant and help meet the demanding needs of clinical and translational research.
Big Data and Cloud Storage
The decreasing cost of modern sequencing techniques has led to an increased demand for data storage, compression, and analytics expertise. TRI meets these needs by implementing cloud computing solutions, enabling high-performance processing of large genomic datasets, and assisting clients with the installation and configuration of their own in-house genomics core. TRI is ISO:27001-certified in information security, and is in compliance with National Institute of Standards and Technology (NIST) and Federal Information Security Management Act (FISMA) security requirements.